CLINICAL CHEMISTRY 1 QUIZ

1.-3 list the different blood specimens.

4. What is the color of the vacutainer tube with no anticoagulant?

5. Name one specific topic in lab math..

6. -8. Name three methods of ensuring reliability of results.

9. Term to describe dark yellow appearance of serum.

10. Term to describe light yellow color of serum

11. Supernatant fluid obtained after centrifugation of clotted blood.

12. Supernatant fluid obtained after centrifugation of un-clotted blood.

13. Most preferred blood sample used in CC.

14. What is the significance of using quality assurance in the clinical laboratory?

15. The most predominant monosaccharide in man.

16. The simplest form of lipid.

17. Name one substance tested in RFT.

18. Transcribe RFT.

19-20. Describe completely how a hemolyzed serum looks like.

20-25. Discuss at least three tests involved in the history of CC.

 ANSWERS NEXT WEEK.

CC3 Review Questions on Toxicology– Answers to Quiz

1.      Test for 17- hydroxycorticosteroids

Porter-Silber

2.      The 2 antibodies present in Hashimoto’s thyroiditis

Anti-microsomal

Anti-thyroglobulins

3.      Exophthalmos is present in what condition?

Hyperthyroidism

4.      The major metabolite of epinephrine and norepinephrine

Vanillylmandelic acid

5.      The method that test for the ability of the thyroid gland to trap iodine.

RAUI

6.      The 2 major metabolic hormones

T3 and T4

7.      Ideal sample for steroid testing

24-hr urine sample that has been detoxified

8.      It is characterized by thyroid gland enlargement

Goiter

9.      Test for 17 ketosteroids

Zimmerman

10.  2 clinical significance of elevated catecholamines

Neuroblastoma

Pheochromocytoma

CC3 Review Questions on Endocrinology– Answers to Quiz

1. Hormone that helps in contracting uterus during delivery.
Oxytocin 
2. Hormone that helps in milk production
Prolactin (PrL or PRL) 
3. Mechanism by which steroid hormones function
Mechanism 2 or internal binding 
4. Mechanism by which peptide hormones function
Mechanism 1 or binding at the cell surface 
5. Another term for hormones
Chemical messengers 
6. 4 types of hormones according to chemical structure
Amino acids, peptide/proteins, steroid, eicosanoids 

Image credit: endocrinesurgery.ucla.edu

CC 3 Review Questions-Endocrinology (Answers to Quiz)

CC 3 Review Questions-Endocrinology (Answers to Quiz)

Set A

1.      Major difference of a hormone from an enzyme.

A hormone is an initiator of biochemical reactions, while an enzyme is a catalyst.

2.      The hormone tested in pregnancy test

Human Chorionic Gonadotropic Hormone (HCG)

3.      Hormone responsible for contraction of uterus during the birthing process.

oxytocin

4.      Also called somatostatin

Growth Hormone Inhibitory Hormone (GHIH or GHIF)

5.      Also called the master gland

Pituitary gland

6.      Function of FSH

Egg/sperm production

7.      Hormone that helps retain water or maintain water-electrolyte balance

Antidiuretic hormone (ADH), aldosterone

8.      Amino acid base of thyroid hormones

Tyrosine

9.      Anterior pituitary hormones

FSH, ACTH, FSH, LH, PrL, GH

Set B

1.       3 Hormones produced by thyroid gland

T3, T4, calcitonin

2.      Major carrier protein of thyroid hormones

TBG

3.      Where is acridinium ester used in TFT?

Automated method

4.      3 carrier proteins for thyroid hormones

Albumin, TBPA, TBG

5.      Pathway for T3, T4 secretion.

T3, T4 concentration acts as the stimulus for increased or decreased TRH secretion. TRH acts on anterior pituitary to increase or decrease secretion of TSH. TSH stimulates the thyroid gland to increase or decrease secretion of T3 and T4 returning their concentrations back to normal and homeostasis is achieved.

6.      Solve for FTI if TT4 = 10 mg/dL, and THBR = 20%

FTI = TT4 X THBR

FTI = 10 X (20/30)

FTI = 6.67 mg/dL

7.      Two methods for T3.T4 test

RIA, EMIT, EQUILIBRIUM DIALYSIS ,ETC.

ENZYME REVIEW QUESTIONS IN CLINICAL CHEMISTRY 2

MATCHING TYPE: MATCH COLUMN B WITH COLUMN A  (WRITE CAPITAL LETTERS ON A WHOLE SHEET OF YELLOW PAPER.

ANSWERS

 COLUMN A                                            COLUMN B

SUBSTANCE TESTED	NORMAL VALUES (CHOICES)
3.  AST - E	A. < 2 mg/dL
4.  ACP - A	B.  < 1 /umol/L
5.  ALT - E	C.  15-165 U/L
6.  LDH - I-..Less..than..200.U/L	D.  90-190 U/L
7.  Glucose   - H	E.  35- 55 U/L
8. CPK - C	F.  0.3 ug/L
9. Myoglobin – none – (0 to 85 nanograms per milliliter (ng/mL) 10. Troponin I -F	G.  <0 .5="" p="" umol=""> H.  80 -120 mg/dL I. None of the above

SUBSTANCE TESTED	Clinical Significance (CHOICES)
11.  ALP - A	A. bone disease
12.  ACP – B, C, D, E	B.  Paget’s disease
13.  I.P. - A	C.  Breast cancer
14  LDH – E,G,H	D.  Prostate cancer
15.  Glucose    - F	E.  Megaloblastic anemia
16. AST – G, H	F. DM
17. ALT - G 18. LDH –E,G,H 19. CK - H	G.  hepatitis H.  Myocardial infarction I. None of the above

SUBSTANCE TESTED	Substrate (CHOICES)
20.  ALP – B, C, F, G	A. creatine
21.  ACP – B, C, F, G	B.  PNPP
22.  I.P. - I - not an enzyme	C.  Betaglycero phosphate
23  LDH - E	D.  alpha ketoglutarate
24.  Glucose    - I - not an enzyme	E.  lactate
25. AST – D, G,	F.  PNP
26. ALT – D 27  TB - I - not an enzyme 28. CK - A 29. myglobin -I - not an enzyme 30. Troponin I and T -I - not an enzyme	G.  aspartate H. umbilleferone phosphate I. None of the above

1. Discuss 3 Precautions for ACP test.(Specific) READ,,NOTES
2. Discuss 3 precautions for ALP test. .(Specific)
3. Discuss 3 precautions for LDH test. .(Specific)