Tuesday, March 22, 2011

Bilirubin Review Exam Questions

INDICATE WHETHER:

INCREASE B1, INCREASE TB = A

INCREASE B2, INCREASE TB = B

INCREASE B1 & B2, INCREASE TB = C

NONE OF THE ABOVE = D

1. 1. Obstruction of the biliary tract

  1. Hepatic encephalopathy
  2. EBF
  3. Infectious Hepatitis
  4. HDN
  5. Liver carcinoma
  6. Gilbert’s syndrome
  7. Reye’s disease
  8. Hepatitis B infection
  9. Kernicterus

Where:

TB- TOTAL BILIRUBIN

B1 – Bilirubin 1

B2 – Bilirubin 2


ANSWERS FOUND IN THIS POST.


Friday, March 18, 2011

Answers to Normality, Molarity Problem Solving Review Questions in Clinical Chemistry

PROBLEM SOLVING :

1. WRITE DOWN FORMULA.
2. SHOW COMPUTATIONS.
3. ENCLOSE ANSWERS IN BOXES.

ATOMIC WEIGHTS:

Na = 23 H = 1 S = 32
Cl= 35.5 O = 16

1. If you weigh 5 g NaCl solution and dissolve it in 1000 ml of diluent. ( 5 pts. each)

A. What is the Molarity?

M= Gram molecular weight per liter of solution, hence: M= 5 /58.5/1 liter

M = 0.085 M

B. What is the Normality?

Since Normality (N) = M x valence(factor)

M = 0.085 x 1 (valence)

M = 0.085 N

N.B. WHEN THE VALENCE OR FACTOR IS ONE THE NORMALITY IS EQUIVALENT TO THE MOLARITY.

C. What is the percent solution?

% = Weight/total volume x 100

% = (5/1,000 mL) X 100

% = 0.5%

ANSWERS TO THE REMAINING QUESTIONS WILL BE GIVEN NEXT POST.

2. What is the Molarity of a 0.5 N H2SO4 solution? (5 pts.)
3. What is the dilution if you add 0.75 ml of serum to 3.0 ml of diluent? ( 5 pts.)
4. How would you prepare 1:20 serum dilution? (5 pts.)
5. How would you prepare a 0.5 % NaCl solution? (5 pts.)
6. You are asked to prepare 200 ml of the following standard concentrations from a 20 mg/dL standard stock solution: Tabulate volume of solute and solvent and also dilution. ( 5 pts. each)

A. 2 mg/dL C. 8 mg/dL
B. 4 mg/dL D. 10 mg/dL
E. 15 mg/dL



Thursday, March 17, 2011

Answers to Clinical Chemistry Review Questions - Blood Gas Analysis

Clinical Chemistry Review Questions vary in difficulty and complexity. Here are some basic questions which can help you review common principles in Clinical Chemistry.

Select the BEST ANSWER.

1. The most common sample specimen in clinical chemistry is:

a. Plasma c. whole blood

b. Serum d. buffy coat

2. In enzyme analysis, the following should be monitored closely, EXCEPT:

a. Temperature c. pH

b. Concentration of substrate d. non-competitive inhibitor

3. Electrolytes are called amphoteric substances because of this reason:

a. They can either be negatively or positively charged

b. They can be water or non-water soluble

c. They can transform from one energy form to another

d. They are directly transported in the blood stream.

4. The following statements are true of electrophoresis, EXCEPT:

a. It is a method to separate proteins from one another

b. The media can be paper, agar gel or cellulose

c. The principle depends upon their ability to fluoresce

d. Electrophoretic mobility is based on the charges of the ions.

5. In the maintenance of normal blood pH, these two organs are involved:

a. Lungs and heart c. lungs and kidneys

b. Kidneys and heart d. kidneys and liver

Choices for numbers 6 to 10

a. Uncompensated metabolic alkalosis

b. Uncompensated metabolic acidosis

c. Uncompensated respiratory alkalosis

d. Uncompensated respiratory acidosis

e. Partially compensated metabolic alkalosis

f. Partially compensated metabolic acidosis

g. Partially compensated respiratory alkalosis

h. Partially compensated respiratory acidosis

i. Fully compensated metabolic alkalosis

j. Fully compensated metabolic acidosis

k. Fully compensated respiratory alkalosis

l. Fully compensated respiratory acidosis

m. None of the above

6. Given pH – 7.49, pCO2= 40 mmHg, HCO3 = 32 mmol/L, What do these values indicate?- partially compensated metabolic alkalosis

7. Given pH – 6.8, dCO2= 10 mmol/L, TCO2= 22 mmol/L, What do these values indicate?- partially compensated respiratory acidosis

8. Given pH- 7.43, HCO3= 29 mmol/L, pCO2 – 50 mmHg. What do these values indicate?- Fully compensated metabolic alkalosis

-

9. Given pH- 7.15, HCO3= 25 mmol/L, pCO2 – 60 mmHg. What do these values indicate? - Uncompensated respiratory acidosis.

-

U10. Given pH- 7.50, HCO3= 40 mmol/L, pCO2 – 40 mmHg. What do these values indicate?

- Uncompensated metabolic alkalosis

Sunday, March 13, 2011

Clinical Chemistry Review Questions

Clinical Chemistry Review Questions vary in difficulty and complexity. Here are some basic questions which can help you review common principles in Clinical Chemistry.

Select the BEST ANSWER.

1. The most common sample specimen in clinical chemistry is:

a. Plasma c. whole blood

b. Serum d. buffy coat

2. In enzyme analysis, the following should be monitored closely, EXCEPT:

a. Temperature c. pH

b. Concentration of substrate d. non-competitive inhibitor

3. Electrolytes are called amphoteric substances because of this reason:

a. They can either be negatively or positively charged

b. They can be water or non-water soluble

c. They can transform from one energy form to another

d. They are directly transported in the blood stream.

4. The following statements are true of electrophoresis, EXCEPT:

a. It is a method to separate proteins from one another

b. The media can be paper, agar gel or cellulose

c. The principle depends upon their ability to fluoresce

d. Electrophoretic mobility is based on the charges of the ions.

5. In the maintenance of normal blood pH, these two organs are involved:

a. Lungs and heart c. lungs and kidneys

b. Kidneys and heart d. kidneys and liver

Choices for numbers 6 to 10

a. Uncompensated metabolic alkalosis

b. Uncompensated metabolic acidosis

c. Uncompensated respiratory alkalosis

d. Uncompensated respiratory acidosis

e. Partially compensated metabolic alkalosis

f. Partially compensated metabolic acidosis

g. Partially compensated respiratory alkalosis

h. Partially compensated respiratory acidosis

i. Fully compensated metabolic alkalosis

j. Fully compensated metabolic acidosis

k. Fully compensated respiratory alkalosis

l. Fully compensated respiratory acidosis

m. None of the above

6. Given pH – 7.49, pCO2= 40 mmHg, HCO3 = 32 mmol/L, What do these values indicate?

7. Given pH – 6.8, dCO2= 10 mmol/L, TCO2= 22 mmol/L, What do these values indicate?

8. Given pH- 7.43, HCO3= 29 mmol/L, pCO2 – 50 mmHg. What do these values indicate?

9. Given pH- 7.15, HCO3= 25 mmol/L, pCO2 – 60 mmHg. What do these values indicate?

10. Given pH- 7.50, HCO3= 40 mmol/L, pCO2 – 40 mmHg. What do these values indicate?



Friday, March 11, 2011

Transcribe the following Terms in Clinical Chemistry

Transcribe the following:

H-H equation -
G6PD -
5'NT -
OCT-
PNP-
CHS-
CK-
LPL-
FFA-
CHD-

Tuesday, March 8, 2011

ANSWERS to Lipids Quiz- Exam Review Questions

ANSWERS to Lipids Quiz- Exam Review Questions

Identify the following items:

1.__Phospholipids__ It is the lipid component of the lungs that prevents the lungs from collapsing.

2.__High Density Lipoprotein or HDL__ It is also called the good cholesterol.

3.__Low Density Lipoprotein or LDL___ It is also called the bad cholesterol.

4.__High Density Lipoprotein__ It is considered as the lipoprotein with the highest density.

5.__chylomicrons__ The lipid that stays at the point of origin in electrophoresis.

6.___chylomicrons___ It causes lipemia of serum.

7.___triglycerides___ The food sources of this lipid is meat fat.

8.___triglycerides___ The conversion factor of this lipid, from traditional to S.I. units is 0.01129.

9.___fatty acids____ It is the simplest form of lipid.

10.__cholesterol__It is the basic nucleus of most steroid hormones

Clinical Chemistry Case Study


An elderly male patient was brought to the emergency room complaining of nausea, vomiting and body malaise. He was afebrile and had a blood pressure of 150/100.
The laboratory results were as follows:
Total cholesterol – 1.87 mmol/L
Triglycerides – 1.3 mmol/L
Glucose = 3.8 mmol/L
Hemoglobin = 150 mg/dL
Hematocrit 52 vol%

QUESTIONS:
1. What is the initial impression based on lab results?
2. What further laboratory testing or diagnostic procedure do you recommend?
3. Defend your answers.

ANSWERS:

1. Primary hypertension
2. Cardiac panel test, to include CKMB, AST, LDH, Troponin
 CBC, routine urinalysis, Kidney function tests (BUN, creatinine) could also be performed to rule out other causes.
3. The lab results are normal, so there are no underlying lipid cause, but the BP is slightly elevated, so it is primary hypertension or essential hypertension.

Chitika

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